Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10764283 | 0.94 | CA12 (0.41) | CA12CA2CA9PPARGBCHE | |
| SCHEMBL13645984 | 0.81 | SIGMAR1 (0.48) | CA12CA2CA9PPARGBCHE | |
| SCHEMBL11145951 | 0.81 | CA12 (0.47) | CA12CA2CA9PPARGBCHE | |
| SCHEMBL151367 | 0.81 | KCNA3 (0.43) | CA12CA2CA9PPARGBCHE | |
| SCHEMBL2484113 | 0.81 | PPARG (0.38) | CA12CA2CA9PPARGBCHE | |
| SCHEMBL17766657 | 0.81 | CYP3A4 (0.39) | CA12CA2CA9PPARGBCHE | |
| SCHEMBL10695564 | 0.80 | KCNA3 (0.42) | MEN1KMT2AL3MBTL1SIGMAR1 | |
| SCHEMBL17037834 | 0.79 | SIGMAR1 (0.52) | CA12CA2CA9PPARGBCHE | |
| SCHEMBL14851194 | 0.78 | CA12 (0.41) | CA12CA2CA9PPARGBCHE | |
| SCHEMBL10695735 | 0.77 | AOC3 (0.36) | MEN1HTTKMT2AUSP2AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252482-A2 | 7-Acyloxy-6-aminoacyloxypolyoxylabdanes, process for their preparation and their use as medicine | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-13 | — | — | EP | disclosed |