Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695304 | 0.84 | BCHE (0.47) | DRD2ACHEADRB2KMT2A | |
| SCHEMBL10427011 | 0.82 | CYP3A4 (0.58) | SMPD1DRD2KDM4EMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL9782076 | 0.76 | SLC2A1 (0.65) | POLBKDM4ESLC2A1ATMADRB2 | |
| Hydrochloric Acid SCHEMBL10702648 | 0.76 | DRD2 (0.52) | SMPD1DRD2POLBKDM4ESLC2A1 | |
| SCHEMBL11811971 | 0.75 | SLC2A1 (0.68) | SMPD1DRD2POLBKDM4ESLC2A1 | |
| SCHEMBL10696001 | 0.75 | ACHE (0.51) | ACHE | |
| SCHEMBL10427024 | 0.74 | CYP3A4 (0.46) | SMPD1DRD2ACHEMAPTKMT2A | |
| SCHEMBL10427138 | 0.74 | CYP1A2 (0.46) | SMPD1ACHEMAPT | |
| SCHEMBL27432980 | 0.74 | KDM4E (0.66) | POLBKDM4ESLC2A1ATMADRB2 | |
| SCHEMBL10427068 | 0.72 | CYP3A4 (0.55) | SMPD1KDM4EMAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259782-A1 | Naphthalene and indane derivatives, medicaments containing these compounds and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-03-16 | — | — | EP | disclosed |