Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288660 | 0.73 | HTT (0.43) | ALDH1A1CNR1CNR2 | |
| SCHEMBL10355477 | 0.70 | ALDH1A1 (0.41) | ALDH1A1KMT2A | |
| SCHEMBL5067826 | 0.70 | MEN1 (0.46) | ALDH1A1SIGMAR1MEN1KMT2A | |
| SCHEMBL11888852 | 0.69 | ALDH1A1 (0.56) | ALDH1A1HRH3MEN1KMT2A | |
| SCHEMBL15923278 | 0.69 | CYP2D6 (0.46) | ALDH1A1MEN1KMT2A | |
| SCHEMBL15665132 | 0.69 | CYP2D6 (0.46) | ALDH1A1MEN1KMT2A | |
| SCHEMBL27952439 | 0.69 | CYP2D6 (0.46) | ALDH1A1MEN1KMT2A | |
| SCHEMBL10215060 | 0.68 | ALDH1A1 (0.43) | ALDH1A1HRH3SIGMAR1HSD11B1MEN1 | |
| SCHEMBL1147459 | 0.68 | ALDH1A1 (0.58) | ALDH1A1HRH3MEN1KMT2A | |
| SCHEMBL15664723 | 0.68 | OPRL1 (0.45) | ALDH1A1SIGMAR1HSD11B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253785-A1 | Efficient stereoconservative syntheses of 1-substituted (S)- and (R)-2-aminomethylpyrrolidines and intermediates therein | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1988-01-20 | — | — | EP | disclosed |