Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 6/20 | 0.46 |
| ▸ | PDE4A | P27815 | 4/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CNOT7 | Q9UIV1 | 3/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | BRD2 | P25440 | 1/20 | 0.44 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.44 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.44 |
| ▸ | RGS12 | O14924 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695072 | 0.83 | MEN1 (0.69) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL11058131 | 0.81 | PDE4A (0.62) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL10696644 | 0.78 | ADORA2B (0.65) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL11054535 | 0.78 | PDE4A (0.58) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL11046863 | 0.77 | PDE4A (0.60) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL10696881 | 0.75 | CNOT7 (0.53) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL9842841 | 0.75 | PDE4A (0.49) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL10693464 | 0.75 | PDE4A (0.63) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL10694058 | 0.75 | PDE4A (0.63) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL5174205 | 0.73 | ADORA2B (0.51) | ADORA2BPDE4AADORA2APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260127-A2 | Xanthine derivatives, their preparation and pharmaceutical compositions containing them | BEECHAM - WUELFING GmbH & Co. KG (DE) | 1988-03-16 | — | — | EP | disclosed |