Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 6/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.49 |
| ▸ | PDE4A | P27815 | 3/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | BRD2 | P25440 | 1/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.47 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PARN | O95453 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696644 | 0.82 | ADORA2B (0.65) | CNOT7ADORA2BPDE4AADORA2APDE4B | |
| SCHEMBL10695216 | 0.81 | MEN1 (0.75) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL5606734 | 0.79 | PDE4A (0.67) | CNOT7ADORA2BPDE4AADORA2APDE4B | |
| SCHEMBL10693202 | 0.76 | PDE4A (0.63) | CNOT7ADORA2BPDE4AADORA2APDE4B | |
| SCHEMBL5174205 | 0.76 | ADORA2B (0.51) | CNOT7ADORA2BPDE4AADORA2APDE4B | |
| SCHEMBL10695023 | 0.76 | PDE4A (0.63) | CNOT7ADORA2BPDE4AADORA2APDE4B | |
| SCHEMBL10696193 | 0.76 | PDE4A (0.46) | CNOT7ADORA2BPDE4AADORA2APDE4B | |
| SCHEMBL9293720 | 0.76 | CNOT7 (0.45) | CNOT7ADORA2BPDE4AADORA2APDE4B | |
| SCHEMBL6357569 | 0.76 | LMNA (0.52) | CNOT7ADORA2BPDE4AADORA2APDE4B | |
| SCHEMBL6344281 | 0.76 | LMNA (0.52) | CNOT7ADORA2BPDE4AADORA2APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260127-A2 | Xanthine derivatives, their preparation and pharmaceutical compositions containing them | BEECHAM - WUELFING GmbH & Co. KG (DE) | 1988-03-16 | — | — | EP | disclosed |