Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 4/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10426964 | 0.89 | ACHE (0.54) | ACHE | |
| SCHEMBL10427028 | 0.89 | CYP3A4 (0.54) | CYP3A4CYP1A2CYP2D6ACHEBLM | |
| Hydrochloric Acid SCHEMBL10427196 | 0.89 | ACHE (0.54) | ACHE | |
| SCHEMBL10695000 | 0.84 | CDK8 (0.55) | CYP3A4CYP1A2CYP2D6ACHE | |
| SCHEMBL6632239 | 0.84 | ACHE (0.50) | ACHE | |
| Hydrochloric Acid SCHEMBL4861583 | 0.83 | ACHE (0.49) | ACHE | |
| Hydrochloric Acid SCHEMBL10427943 | 0.83 | ACHE (0.48) | ACHE | |
| SCHEMBL10696001 | 0.83 | ACHE (0.51) | ACHE | |
| SCHEMBL13987568 | 0.81 | ACHE (0.55) | ACHE | |
| SCHEMBL13987570 | 0.81 | ACHE (0.49) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259782-A1 | Naphthalene and indane derivatives, medicaments containing these compounds and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-03-16 | — | — | EP | disclosed |