Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 8/20 | 0.47 |
| ▸ | MAOB | P27338 | 6/20 | 0.46 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.44 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691942 | 0.90 | XDH (0.49) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL10693667 | 0.89 | MAOB (0.53) | CYP1B1MAOBSTAT3MAOA | |
| SCHEMBL9462345 | 0.75 | MAPT (0.46) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL9462343 | 0.75 | MAPT (0.46) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL8786824 | 0.73 | GSK3B (0.38) | HPGD | |
| SCHEMBL13203405 | 0.70 | CYP1B1 (0.81) | MAPTRAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL30613493 | 0.70 | PARP1 (0.42) | KMT2AMEN1LMNASMN1; SMN2MAOB | |
| SCHEMBL10693327 | 0.69 | XDH (0.49) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL10694710 | 0.69 | XDH (0.49) | MAPTNPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL7997434 | 0.68 | MAPT (1.00) | MAPTNPC1RAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4778792-A | Use of 7-acyl benzoxazinones and their derivatives in treating atheromatous disorders | LABORATORIES NEGMA (FR) | 1988-10-18 | — | — | US | disclosed |