Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA7 | P43166 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 6/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.35 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697493 | 0.90 | ABCC9 (0.40) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL7267578 | 0.88 | ABCC9 (0.42) | ALDH1A1MAPTRECQLCA12CA1 | |
| SCHEMBL10694873 | 0.86 | ABCC9 (0.41) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL10694956 | 0.85 | ABCC9 (0.41) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL10695982 | 0.83 | ABCC9 (0.39) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9300265 | 0.83 | ABCC9 (0.53) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9300267 | 0.83 | ABCC9 (0.53) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9300262 | 0.83 | ABCC9 (0.53) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL8090590 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MAPTRECQLCA12CA1 | |
| SCHEMBL10697093 | 0.80 | ALDH1A1 (0.40) | ALDH1A1MAPTRECQLCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273262-A2 | Chroman derivatives | MERCK PATENT GmbH (DE) | 1988-07-06 | — | — | EP | disclosed |