Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28159200 | 0.85 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28393066 | 0.79 | CYP3A4 (0.41) | ALDH1A1HSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12124965 | 0.78 | ESR1 (0.48) | CYP2C9CYP2C19TSHRL3MBTL1CYP3A4 | |
| SCHEMBL11511564 | 0.77 | MEN1 (0.40) | ALDH1A1HSD17B10TSHRL3MBTL1CYP3A4 | |
| SCHEMBL6816261 | 0.77 | MAPT (0.40) | ALDH1A1HSD17B10CYP1A2TSHRL3MBTL1 | |
| SCHEMBL29557654 | 0.77 | ALDH1A1 (0.43) | ALDH1A1HSD17B10CYP1A2CYP2C9TSHR | |
| SCHEMBL9515383 | 0.77 | ALDH1A1 (0.43) | ALDH1A1HSD17B10CYP1A2CYP2C9TSHR | |
| SCHEMBL29558024 | 0.77 | ALDH1A1 (0.43) | ALDH1A1HSD17B10CYP1A2CYP2C9TSHR | |
| SCHEMBL22824154 | 0.76 | CASP1 (0.44) | ALDH1A1CYP1A2L3MBTL1CYP3A4CASP1 | |
| SCHEMBL14956637 | 0.76 | TSHR (0.35) | ALDH1A1TSHRL3MBTL1ADRA2BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257591-A2 | Process for preparing diphenylalkene derivatives | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1988-03-02 | — | — | EP | disclosed |
| US-4480008-A | Solid polymer binders for thermosetting powder coating compositions, powder coating compositions containing these binders and metal objects coated with these coating compositions | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-10-30 | — | — | US | disclosed |