Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20503396 | 0.79 | CYP4F2 (0.40) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| SCHEMBL11201754 | 0.76 | ALDH1A1 (0.45) | ALDH1A1TSHREGLN1NPSR1GLO1 | |
| SCHEMBL6678513 | 0.75 | TSHR (0.44) | ALDH1A1TSHRCYP2D6MEN1KMT2A | |
| SCHEMBL7069570 | 0.72 | EGLN1 (0.37) | ALDH1A1TSHREGLN1NPSR1GLO1 | |
| SCHEMBL27350419 | 0.72 | CYP4F2 (0.38) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| SCHEMBL9719100 | 0.72 | CYP4F2 (0.44) | ALDH1A1TSHRLMNAHSD17B10MEN1 | |
| SCHEMBL27486109 | 0.72 | CYP4F2 (0.44) | ALDH1A1TSHREGLN1NPSR1GLO1 | |
| Ammonia Solution, Strong SCHEMBL27650220 | 0.70 | CYP4F2 (0.42) | ALDH1A1TSHREGLN1NPSR1GLO1 | |
| SCHEMBL289488 | 0.69 | ALDH1A1 (0.38) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL3853357 | 0.69 | ALDH1A1 (0.46) | ALDH1A1TSHREGLN1NPSR1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0274379-A2 | Process for preparing pyridine-2,3-dicarboxylic acid compounds | SUGAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-07-13 | — | — | EP | disclosed |