Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678513 | 0.86 | TSHR (0.44) | ALDH1A1TSHRTP53MEN1CYP1A2 | |
| SCHEMBL9766503 | 0.80 | ALDH1A1 (0.35) | ALDH1A1TSHRTP53MEN1CYP1A2 | |
| SCHEMBL31150640 | 0.75 | ALDH1A1 (0.35) | ALDH1A1TSHRTP53 | |
| SCHEMBL10820962 | 0.75 | CA4 (0.39) | TSHRFFAR3 | |
| SCHEMBL9370436 | 0.75 | ALDH1A1 (0.35) | ALDH1A1TSHRTP53MEN1CYP1A2 | |
| SCHEMBL17224645 | 0.75 | ALDH1A1 (0.35) | ALDH1A1TSHRTP53MEN1CYP1A2 | |
| SCHEMBL27554006 | 0.75 | FDPS (0.41) | ALDH1A1TSHRTP53MEN1KMT2A | |
| SCHEMBL16445975 | 0.73 | FDPS (0.46) | — | |
| SCHEMBL3711104 | 0.73 | CES2 (0.36) | ALDH1A1TSHRTP53MEN1CYP1A2 | |
| SCHEMBL22344279 | 0.73 | ALDH1A1 (0.33) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 468 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210197116-A1 | METHOD OF SCAVENGING ACID SULFIDE SPECIES | INNOSPEC LIMITED (GB) | 2021-07-01 | — | — | US | claimed |
| US-20210198129-A1 | METHODS, PRODUCTS & USES RELATING TO SCAVENGING OF ACIDIC SULFIDE SPECIES | INNOSPEC LIMITED (GB) | 2021-07-01 | — | — | US | claimed |
| EP-3840857-A1 | METHODS, PRODUCTS & USES RELATING TO SCAVENGING OF ACIDIC SULFIDE SPECIES | Innospec Limited (GB) | 2021-06-30 | — | — | EP | claimed |
| EP-3840858-A1 | METHOD OF SCAVENGING ACID SULFIDE SPECIES | Innospec Limited (GB) | 2021-06-30 | — | — | EP | claimed |
| CN-108218702-B | Preparation method of 2-fluoro ethyl acetoacetate | 湖北卓熙氟化股份有限公司 | 2020-10-09 | — | — | CN | claimed |
| WO-2020039200-A1 | METHODS, PRODUCTS & USES RELATING TO SCAVENGING OF ACIDIC SULFIDE SPECIES | INNOSPEC LIMITED (GB) | 2020-02-27 | — | — | WO | claimed |
| WO-2020039199-A1 | METHOD OF SCAVENGING ACID SULFIDE SPECIES | INNOSPEC LIMITED (GB) | 2020-02-27 | — | — | WO | claimed |
| US-20200040108-A1 | PROCESS FOR MAKING A CONSUMER PRODUCT COMPRISING MODIFIED POLYSACCHARIDES | PROCTER & GAMBLE INTERNATIONAL OPERATIONS SA | 2020-02-06 | — | — | US | claimed |
| WO-2020026143-A1 | PROCESS FOR MAKING A CONSUMER PRODUCT COMPRISING MODIFIED POLYSACCHARIDES | PROCTER & GAMBLE INTERNATIONAL OPERATIONS SA (CH) | 2020-02-06 | — | — | WO | claimed |
| EP-3604346-A1 | PROCESS FOR MAKING A CONSUMER PRODUCT COMPRISING MODIFIED POLYSACCHARIDES | Procter & Gamble International Operations SA (CH) | 2020-02-05 | — | — | EP | claimed |
| WO-2014108919-A2 | NOVEL INTERMEDIATE AND POLYMORPHS OF 1-(4-METHOXYPHENYL)-7-OXO-6-[4-(2-OXOPIPERIDIN-1-YL)PHENYL]-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-c] PYRIDINE-3-CARBOXAMIDE AND PROCESS THEREOF | MSN LABORATORIES LIMITED (IN) | 2014-07-17 | — | — | WO | claimed |
| WO-2014057461-A1 | PROCESS FOR THE PREPARATION OF CRYSTALLINE FORM G OF FEBUXOSTAT | RANBAXY LABORATORIES LIMITED (IN) | 2014-04-17 | — | — | WO | claimed |
| EP-2386548-A2 | Preparation of thionamides | Abbott Laboratories (US) | 2011-11-16 | — | — | EP | claimed |
| US-7541475-B2 | Substituted thiazoles | ABBOTT LABORATORIES (US) | 2009-06-02 | — | — | US | claimed |
| JP-2007500724-A | — | — | 2007-01-18 | — | — | JP | claimed |
| EP-1651624-A2 | PROCESS FOR THE PREPARATION OF SUBSTITUTED THIAZOLES | Abbott Laboratories (US) | 2006-05-03 | — | — | EP | claimed |
| US-20050075503-A1 | Substituted thiazoles | ABBVIE INC. | 2005-04-07 | — | — | US | claimed |
| WO-2005012273-A2 | PROCESS FOR THE PREPARATION OF SUBSTITUTED THIAZOLES | ABBOTT LABORATORIES (US) | 2005-02-10 | — | — | WO | claimed |
| US-20050027128-A1 | Substituted thiazoles | ABBOTT LABORATORIES | 2005-02-03 | — | — | US | claimed |
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050027128-A1 | Substituted thiazoles | XDH, TH, TPI1 | ALDH1A1 313/4885TSHR 1022/4885TP53 4246/4885 |
| US-20050075503-A1 | Substituted thiazoles | XDH, TH, TPI1 | ALDH1A1 313/4885TSHR 1022/4885TP53 4246/4885 |
| US-20200040108-A1 | PROCESS FOR MAKING A CONSUMER PRODUCT COMPRISING MODIFIED POLYSACCHARIDES | MGAM, FUT5, FUT6 | ALDH1A1 464/4885TSHR 1930/4885TP53 4085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.