Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.57 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | TYR | P14679 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL830794 | 1.00 | TSHR (0.67) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28124478 | 0.94 | TSHR (0.75) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28067703 | 0.94 | TSHR (0.75) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL319125 | 0.94 | TSHR (0.75) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL252928 | 0.94 | TSHR (0.75) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL15153931 | 0.93 | TSHR (0.57) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL16029608 | 0.93 | TSHR (0.57) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28813030 | 0.92 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL29085649 | 0.92 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL28496066 | 0.92 | TSHR (0.71) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3612580-A1 | ALIPHATIC THERMOPLASTIC POLYURETHANES, PRODUCTION AND USE THEREOF | Covestro Deutschland AG (DE) | 2020-02-26 | — | — | EP | claimed |
| WO-2024121010-A1 | MULTI-LAYER CONSTRUCTION HAVING GOOD PROPERTIES FOR PRINTING | COVESTRO DEUTSCHLAND AG (DE) | 2024-06-13 | — | — | WO | disclosed |
| EP-3812410-B1 | POLYURETHANE POLYMER HAVING A HARDNESS OF 60 SHORE A OR LOWER AND GOOD ABRASION RESISTANCE | COVESTRO DEUTSCHLAND AG (DE) | 2024-05-29 | — | — | EP | disclosed |
| US-11981095-B2 | Method for producing an at least partially coated object | STRATASYS, INC. (US) | 2024-05-14 | — | — | US | disclosed |
| WO-2024043991-A1 | WATER-RESPONSIVE FILM AND METHODS OF PRODUCING THE SAME | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| WO-2024043992-A1 | ABSORBENT ARTICLES INCLUDING A WATER-RESPONSIVE FILM AND METHODS OF PRODUCING THE SAME | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 2024-02-29 | — | — | WO | disclosed |
| EP-4292818-A2 | COMPOSITE OBJECT COMPRISING A BODY AND A FOAM AND METHOD FOR THE PRODUCTION THEREOF | Stratasys, Inc. (US) | 2023-12-20 | — | — | EP | disclosed |
| EP-3515255-B1 | COMPOSITE OBJECT COMPRISING A BODY AND A FOAM AND METHOD FOR PRODUCING SAME | STRATASYS INC (US) | 2023-12-13 | — | — | EP | disclosed |
| US-11787936-B2 | Polyurethane polymer having a hardness of less than or equal to 60 shore A and good abrasion resistance | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2023-10-17 | — | — | US | disclosed |
| EP-4150006-A1 | METHOD FOR PRODUCING THERMOPLASTIC POLYURETHANES | Covestro Deutschland AG (DE) | 2023-03-22 | — | — | EP | disclosed |
| US-20010056170-A1 | Mouldings of thermoplastic polyurethanes exhibiting reduced fogging | BAYER AKTIENGESELLSCHAFT (DE) | 2001-12-27 | — | — | US | disclosed |
| US-20010044516-A1 | Aliphatic thermoplastic polyurethanes and use thereof | COVESTRO DEUTSCHLAND AG (DE) | 2001-11-22 | — | — | US | disclosed |
| US-6166135-A | Aliphatic sinterable thermoplastic polyurethane moulding compositions of reduced mechanical strength | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-26 | — | — | US | disclosed |
| US-5925697-A | MOLDING MATERIALS FOR MOLDINGS AND COSMETICS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-07-20 | — | — | US | disclosed |
| US-5567791-A | CONTROLLING CONCENTRATION OF CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-22 | — | — | US | disclosed |
| US-5527602-A | Laminates of graft polymer and thermoplastic polyurethane | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-18 | — | — | US | disclosed |
| US-5430121-A | Thermoplastic polyurethanes modified by siloxane block copolymers | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-04 | — | — | US | disclosed |
| US-5218058-A | Flexible elastic polyurethane films a process for their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1993-06-08 | — | — | US | disclosed |
| US-5200491-A | Reacting a hydroxy-terminated polyol and a diisocyanate in the presence of a phosphorous compound metal deactivator | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-06 | — | — | US | disclosed |
| US-4526952-A | Incorporating carbon black into resin | BASF AKTIENGESELLSCHAFT (DE) | 1985-07-02 | — | — | US | disclosed |