Terephthalic Acid

Terephthalic Acid

SCHEMBL830794

C=C.O=C(O)c1ccc(C(=O)O)cc1.OCCO

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.67
TP53 P04637 1/20 0.67
SRD5A2 P31213 4/20 0.57
CA1 P00915 3/20 0.55
CA2 P00918 3/20 0.55
CA12 O43570 1/20 0.55
CA3 P07451 1/20 0.55
TYR P14679 1/20 0.55
DRD1 P21728 1/20 0.55
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
CA14 Q9ULX7 1/20 0.55
CA5B Q9Y2D0 1/20 0.55
DAO P14920 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
ALDH1A1 P00352 3/20 0.52
ALOX15 P16050 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL1069654 1.00 TSHR (0.67) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL28124478 0.94 TSHR (0.75) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL28067703 0.94 TSHR (0.75) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL319125 0.94 TSHR (0.75) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL252928 0.94 TSHR (0.75) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL15153931 0.93 TSHR (0.57) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL16029608 0.93 TSHR (0.57) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL28813030 0.92 TSHR (0.71) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL29085649 0.92 TSHR (0.71) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL28496066 0.92 TSHR (0.71) TSHRTP53SRD5A2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150329667-A1 Process For Manufacturing Polyethylene Terephthalate CLARIANT FINANCE (BVI) LIMITED (VG) 2015-11-19 US claimed
EP-2331313-A1 METHOD OF MAKING A CONTAINER SUCH AS A BOTTLE FROM A PREFORM MADE OF THERMOPLASTIC POLYMER Nestec S.A. (CH) 2011-06-15 EP claimed
WO-2010034766-A1 METHOD OF MAKING A CONTAINER SUCH AS A BOTTLE FROM A PREFORM MADE OF THERMOPLASTIC POLYMER NESTEC S.A. (CH) 2010-04-01 WO claimed
EP-2168751-A1 Method of making a container such as a bottle from a preform made of thermoplastic polymer NESTEC S.A. (CH) 2010-03-31 EP claimed
WO-2024062774-A1 POLYESTER RESIN, BINDER FOR PIGMENT PRINTING, INK FOR PIGMENT PRINTING, AND PRODUCTION METHOD FOR POLYESTER RESIN 日華化学株式会社 2024-03-28 WO disclosed
US-20230383471-A1 ABSORBENT PAPER PRODUCTS HAVING UNIQUE PHYSICAL STRENGTH PROPERTIES MERCER INTERNATIONAL INC (CA) 2023-11-30 US disclosed
US-20230323606-A1 ABSORBENT PAPER PRODUCTS HAVING UNIQUE PHYSICAL STRENGTH PROPERTIES MERCER INTERNATIONAL INC (CA) 2023-10-12 US disclosed
US-11674267-B2 Absorbent paper products having unique physical strength properties MERCER INTERNATIONAL INC. (CA) 2023-06-13 US disclosed
US-11668053-B2 Absorbent paper products having unique physical strength properties MERCER INTERNATIONAL INC. (CA) 2023-06-06 US disclosed
US-20230089078-A1 POLYESTER RESIN AND PRODUCTION METHOD THEREFOR UNITIKA LTD. (JP) 2023-03-23 US disclosed
US-11111344-B2 Process for making absorbent towel and soft sanitary tissue paper webs having nanofilaments MERCER INTERNATIONAL INC. (CA) 2021-09-07 US disclosed
EP-3478893-B1 DIFFERENTIAL-DENSITY PAPER PRODUCTS COMPRISING CELLULOSE NANOFILAMENTS MERCER INT INC (CA) 2021-08-04 EP disclosed
US-20040086733-A1 Polyester resin, molded product made thereof and process for production of polyester resin MITSUBISHI CHEMICAL CORPORATION (JP) 2004-05-06 US disclosed
US-6703474-B2 USING COMPOSITE OXIDE CATALYST MITSUBISHI CHEMICAL CORPORATION (JP) 2004-03-09 US disclosed
US-20030144459-A1 Polyester resin, molded product made thereof and process for production of polyester resin MITSUBISHI CHEMICAL CORPORATION (JP) 2003-07-31 US disclosed
EP-1281725-A1 POLYESTER RESIN, MOLDED ARTICLE THEREOF, AND PROCESS FOR PRODUCING POLYESTER RESIN MITSUBISHI CHEMICAL CORPORATION (JP) 2003-02-05 EP disclosed
US-20030013042-A1 Polymeric film having a coating layer of a phosphonic acid group containing polymer BRABBS NOEL STEPHEN (LU) 2003-01-16 US disclosed
US-6495309-B1 GELATION FREE COOLYMER OF SUCH AS ACRYLIC ACID, VINYL PHOSPHONIC ACID AND SODIUM VINYL SULPHONATE ON A LITHOGRAPHIC PRINTING PLATE E.I. DU PONT DE NEMOURS AND COMPANY 2002-12-17 US disclosed
US-6160085-A Polyester and process for its production MITSUBISHI CHEMICAL CORPORATION (JP) 2000-12-12 US disclosed
US-4096124-A TEREPHTHALIC ACID, ETHYLENE GLYCOL, TWO-STAGE MOBIL OIL CORPORATION (US) 1978-06-20 US disclosed