Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10708155 | 0.90 | PTK2 (0.39) | LMNAMAPTKMT2AMAPK1PTK2 | |
| SCHEMBL10707594 | 0.89 | PTK2 (0.36) | LMNAMAPTKMT2AMAPK1PTK2 | |
| SCHEMBL10700893 | 0.86 | SETD7 (0.41) | LMNAMAPTKMT2AMAPK1MEN1 | |
| SCHEMBL10698960 | 0.86 | MAPT (0.41) | LMNAMAPTKMT2AMAPK1MEN1 | |
| SCHEMBL10696939 | 0.84 | SMN1; SMN2 (0.49) | LMNAMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10696534 | 0.84 | MAPT (0.42) | LMNAMAPTKMT2AMAPK1MEN1 | |
| SCHEMBL10699942 | 0.84 | MAPT (0.51) | LMNAMAPTKMT2AMAPK1MEN1 | |
| SCHEMBL10697943 | 0.83 | MAPT (0.41) | LMNAMAPTKMT2AMAPK1MEN1 | |
| SCHEMBL10701527 | 0.83 | MAPT (0.49) | MAPTKMT2AMAPK1MEN1SMN1; SMN2 | |
| SCHEMBL10696183 | 0.82 | MAPT (0.51) | LMNAMAPTKMT2AMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |