Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 3/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6369684 | 0.86 | CA2 (0.48) | GAAMAPTRAB9ACA2CA9 | |
| SCHEMBL10382794 | 0.79 | ALDH1A1 (0.50) | FYNDRD2DRD1ALDH1A1 | |
| SCHEMBL25555565 | 0.78 | MAPT (0.43) | L3MBTL3GAAMAPTNPC1LMNA | |
| SCHEMBL10383710 | 0.76 | COMT (0.44) | FYNMAPTCA2CA9KDM4E | |
| SCHEMBL6369710 | 0.76 | CA2 (0.44) | GAAMAPTRAB9ACA2CA9 | |
| SCHEMBL10383656 | 0.73 | ABCB1 (0.56) | GAAMAPTRAB9AKMT2AKDM4E | |
| SCHEMBL3506070 | 0.72 | CA2 (0.67) | GAAMAPTRAB9ACA2CA9 | |
| SCHEMBL9203978 | 0.72 | DRD1 (0.42) | FYNMAPTSMN1; SMN2DRD2DRD1 | |
| SCHEMBL22221913 | 0.71 | HRH3 (0.35) | L3MBTL3MEN1KMT2A | |
| SCHEMBL13961198 | 0.71 | DPP8 (0.45) | L3MBTL3MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0275064-A2 | Process for the production of isoindoline derivatives, novel intermediates and process for their production | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-07-20 | — | — | EP | disclosed |