Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27041609 | 0.86 | CYP1A2 (0.59) | CYP1A2CYP2C19SRD5A2CYP2D6HPGD | |
| Water SCHEMBL11468968 | 0.84 | ATM (0.49) | CYP1A2CYP2C19ATMTDP1L3MBTL1 | |
| SCHEMBL30238332 | 0.83 | L3MBTL1 (0.59) | ATMTDP1L3MBTL1PBRM1SRD5A2 | |
| SCHEMBL7488968 | 0.83 | ATM (0.59) | ATMTDP1L3MBTL1PBRM1SRD5A2 | |
| SCHEMBL3684740 | 0.82 | ATM (0.63) | ATMTDP1L3MBTL1PBRM1SRD5A2 | |
| SCHEMBL7325996 | 0.81 | L3MBTL1 (0.57) | ATMTDP1L3MBTL1PBRM1SRD5A2 | |
| SCHEMBL27394550 | 0.81 | ATM (0.57) | ATMTDP1L3MBTL1PBRM1SRD5A2 | |
| SCHEMBL548283 | 0.81 | L3MBTL1 (0.61) | ATMTDP1L3MBTL1PBRM1SRD5A2 | |
| SCHEMBL5377475 | 0.81 | CYP1A2 (0.54) | CYP1A2CYP2C19ALDH1A1CYP2D6KDM4E | |
| SCHEMBL32670780 | 0.80 | SRD5A2 (0.59) | ATMTDP1L3MBTL1PBRM1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4045576-A | ANTI-INFLAMMATORY METHODS USING 2-AMINO-3-(5- AND 6-)BENZOYLPHENYLACETIC ACIDS, ESTERS AND METAL SALTS THEREOF AND THE COMPOUNDS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-08-30 | — | — | US | claimed |
| CN-109180507-B | Ketoprofen hapten, artificial antigen and antibody, and preparation method and application thereof | 北京勤邦生物技术有限公司 | 2022-10-21 | — | — | CN | disclosed |
| EP-3093502-B1 | MICRO FLUID DEVICE | SEKISUI CHEMICAL CO LTD (JP) | 2018-07-04 | — | — | EP | disclosed |
| EP-0255178-A2 | Process for preparing hetero aryl and aryl alkanoic acids | Nobel Chemicals AB (SE) | 1988-02-03 | — | — | EP | disclosed |
| US-4182774-A | Method of inhibiting blood platelet aggregation with 2-amino-3-(5- and 6-)benzoylphenylacetic acids, esters and metal salts thereof | A. H. ROBINS COMPANY, INCORPORATED (US) | 1980-01-08 | — | — | US | disclosed |
| US-4126635-A | ANTICHOLESTEROL, BLOOD PLATELET AGGREGATION INHIBITION | A. H. ROBINS COMPANY, INCORPORATED (US) | 1978-11-21 | — | — | US | disclosed |
| US-4045576-A | ANTI-INFLAMMATORY METHODS USING 2-AMINO-3-(5- AND 6-)BENZOYLPHENYLACETIC ACIDS, ESTERS AND METAL SALTS THEREOF AND THE COMPOUNDS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1977-08-30 | — | — | US | disclosed |