Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | LOX | P28300 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12065517 | 0.85 | LOXL2 (0.54) | TSHRLOXL2RAB9ACA12CA1 | |
| SCHEMBL27041609 | 0.83 | CYP1A2 (0.59) | CYP1A2CYP2C19RAB9ACA12CA1 | |
| SCHEMBL5372608 | 0.83 | TSHR (0.52) | TSHRLOXL2RAB9ACA12CA1 | |
| SCHEMBL1787501 | 0.82 | ACHE (0.59) | TSHRLOXL2RAB9ACA12CA1 | |
| SCHEMBL2892597 | 0.82 | TSHR (0.53) | TSHRLOXL2RAB9ACA12CA1 | |
| SCHEMBL17018477 | 0.81 | LOXL2 (0.54) | TSHRLOXL2RAB9ACA12CA1 | |
| SCHEMBL10696587 | 0.81 | CYP1A2 (0.56) | CYP1A2CYP2C19ALDH1A1PKMKDM4E | |
| SCHEMBL548002 | 0.80 | TSHR (0.52) | TSHRLOXL2RAB9ACA12CA1 | |
| SCHEMBL3933098 | 0.79 | TAS1R3 (0.54) | TSHRLOXL2RAB9ACA12CA1 | |
| SCHEMBL4443803 | 0.78 | LOXL2 (0.58) | TSHRLOXL2RAB9ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205435-B2 | Type B botulism toxin inhibitors | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2007-04-17 | — | — | US | disclosed |
| US-20040176333-A1 | Type b botulism toxin inhibitors | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2004-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176333-A1 | Type b botulism toxin inhibitors | GZMB, CFB, MAOB | CYP1A2 242/4885CYP2C19 320/4885TSHR 2624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.