Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 10/20 | 0.53 |
| ▸ | CNR2 | P34972 | 5/20 | 0.51 |
| ▸ | CNR1 | P21554 | 3/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696568 | 0.88 | ICMT (0.53) | ICMTCNR2CNR1TBXAS1IDO1 | |
| SCHEMBL10696255 | 0.88 | ICMT (0.53) | ICMTCNR2CNR1TBXAS1IDO1 | |
| SCHEMBL10695799 | 0.84 | ICMT (0.49) | ICMTCNR2CNR1TBXAS1IDO1 | |
| SCHEMBL10693439 | 0.82 | CNR2 (0.48) | ICMTCNR2CNR1TBXAS1IDO1 | |
| SCHEMBL20604920 | 0.81 | KDM4E (0.47) | ICMTCNR2CNR1AKR1C3 | |
| SCHEMBL22439157 | 0.76 | ICMT (0.48) | ICMTCNR2CNR1IDO1 | |
| SCHEMBL11893459 | 0.74 | CNR2 (0.67) | ICMTCNR2CNR1 | |
| SCHEMBL27774870 | 0.74 | CNR2 (0.48) | ICMTCNR2CNR1TBXAS1IDO1 | |
| SCHEMBL9236079 | 0.74 | CDC25A (0.70) | ICMTCNR2CNR1 | |
| SCHEMBL13131399 | 0.73 | IDO1 (0.47) | ICMTCNR2CNR1TBXAS1IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252404-A2 | 5-Hydroxy-3-indoleacetic acid fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1988-01-13 | — | — | EP | disclosed |