Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | ICMT | O60725 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KRAS | P01116 | 4/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696722 | 0.84 | CNR2 (0.49) | CNR2ICMTCNR1SMN1; SMN2GAA | |
| SCHEMBL10696568 | 0.82 | ICMT (0.53) | CNR2ICMTCNR1IDO1TBXAS1 | |
| SCHEMBL10696636 | 0.82 | ICMT (0.53) | CNR2ICMTCNR1AKR1C3IDO1 | |
| SCHEMBL10696255 | 0.82 | ICMT (0.53) | CNR2ICMTCNR1AKR1C3IDO1 | |
| SCHEMBL20604920 | 0.82 | KDM4E (0.47) | CNR2ICMTCNR1AKR1C3GAA | |
| SCHEMBL22439157 | 0.79 | ICMT (0.48) | CNR2ICMTCNR1IDO1KRAS | |
| SCHEMBL10695799 | 0.78 | ICMT (0.49) | CNR2ICMTCNR1AKR1C3IDO1 | |
| SCHEMBL12362475 | 0.77 | ICMT (0.38) | CNR2ICMTCNR1AKR1C3GAA | |
| SCHEMBL18554793 | 0.75 | LMNA (0.47) | CNR2CNR1IDO1LMNAKRAS | |
| SCHEMBL29545345 | 0.75 | LMNA (0.47) | CNR2CNR1IDO1LMNAKRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252404-A2 | 5-Hydroxy-3-indoleacetic acid fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1988-01-13 | — | — | EP | disclosed |