Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 9/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.51 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CCR1 | P32246 | 2/20 | 0.48 |
| ▸ | CCR8 | P51685 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL670669 | 0.81 | MAPT (1.00) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL15667134 | 0.80 | MAPT (0.97) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| Water SCHEMBL7195661 | 0.80 | MAPT (0.97) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL16584943 | 0.80 | MAPT (0.97) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL15667133 | 0.80 | MAPT (0.97) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL8937207 | 0.79 | MAPT (0.88) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL9546064 | 0.78 | MAPT (0.75) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL15712118 | 0.77 | ALDH1A1 (0.74) | MAPTALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL27879503 | 0.76 | CCR1 (0.54) | MAPTALDH1A1L3MBTL1SMN1; SMN2HSP90AA1 | |
| SCHEMBL27612640 | 0.75 | PDE10A (0.51) | MAPTALDH1A1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282893-A2 | Pesticides based on 1,10-phenanthrolines | BAYER AG (DE) | 1988-09-21 | — | — | EP | disclosed |