Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30938980 | 0.84 | PDE10A (0.49) | PDE10ASMN1; SMN2ALDH1A1TSHRTDP1 | |
| SCHEMBL34471916 | 0.84 | PDE10A (0.49) | PDE10ASMN1; SMN2ALDH1A1TSHRTDP1 | |
| SCHEMBL11326420 | 0.82 | PDE10A (0.61) | PDE10ASMN1; SMN2ALDH1A1TSHRTDP1 | |
| SCHEMBL29098555 | 0.77 | CYP1A2 (0.46) | PDE10ASMN1; SMN2ALDH1A1TSHRTDP1 | |
| SCHEMBL7795676 | 0.77 | PDE10A (0.60) | PDE10ASMN1; SMN2ALDH1A1TSHRTDP1 | |
| SCHEMBL10390684 | 0.76 | MEN1 (0.59) | PDE10ASMN1; SMN2ALDH1A1TSHRTDP1 | |
| SCHEMBL230859 | 0.76 | RELA (0.59) | PDE10ASMN1; SMN2ALDH1A1TDP1NOS1 | |
| SCHEMBL10696733 | 0.75 | MAPT (0.68) | PDE10ASMN1; SMN2ALDH1A1TDP1HSD17B10 | |
| SCHEMBL862522 | 0.74 | PDE3B (0.47) | ALDH1A1TSHRTDP1HSD17B10MEN1 | |
| SCHEMBL30938978 | 0.72 | ALDH1A1 (0.46) | PDE10ASMN1; SMN2ALDH1A1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1697650-B | Non-nucleoside reverse transcriptase inhibitors | ARDEA BIOSCIENCES INC | 2010-11-10 | — | — | CN | disclosed |
| CN-1697650-A | Non-nucleoside reverse transcriptase inhibitors | RIBAPHARM INC (US) | 2005-11-16 | — | — | CN | disclosed |