Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.63 |
| ▸ | DRD2 | P14416 | 3/20 | 0.61 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.56 |
| ▸ | CCR3 | P51677 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CCR1 | P32246 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697451 | 0.96 | SIGMAR1 (0.65) | SIGMAR1DRD2OPRL1CCR3POLB | |
| SCHEMBL7104448 | 0.81 | SIGMAR1 (0.65) | SIGMAR1DRD2OPRL1CCR3POLB | |
| SCHEMBL9370237 | 0.80 | SIGMAR1 (0.72) | SIGMAR1DRD2OPRL1CCR3POLB | |
| SCHEMBL10761785 | 0.80 | OPRL1 (0.61) | SIGMAR1DRD2OPRL1CCR3POLB | |
| SCHEMBL11062805 | 0.79 | SIGMAR1 (0.70) | SIGMAR1DRD2OPRL1CCR3POLB | |
| SCHEMBL11778752 | 0.79 | SIGMAR1 (0.70) | SIGMAR1DRD2OPRL1CCR3POLB | |
| SCHEMBL7233756 | 0.79 | SIGMAR1 (0.70) | SIGMAR1DRD2OPRL1CCR3POLB | |
| SCHEMBL7986618 | 0.78 | SIGMAR1 (0.60) | SIGMAR1DRD2OPRL1 | |
| Hydrochloric Acid SCHEMBL11073893 | 0.78 | SIGMAR1 (0.68) | SIGMAR1DRD2OPRL1CCR3POLB | |
| SCHEMBL7106817 | 0.78 | OPRL1 (0.60) | SIGMAR1DRD2OPRL1CCR3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252482-A2 | 7-Acyloxy-6-aminoacyloxypolyoxylabdanes, process for their preparation and their use as medicine | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-13 | — | — | EP | disclosed |
| EP-0217372-A2 | Polyoxygenated labdane derivatives, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-08 | — | — | EP | disclosed |