Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.72 |
| ▸ | DRD2 | P14416 | 3/20 | 0.65 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CCR3 | P51677 | 1/20 | 0.58 |
| ▸ | CCR1 | P32246 | 2/20 | 0.56 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11778752 | 0.85 | SIGMAR1 (0.70) | SIGMAR1DRD2OPRL1POLBCCR3 | |
| SCHEMBL11062805 | 0.85 | SIGMAR1 (0.70) | SIGMAR1DRD2OPRL1POLBCCR3 | |
| SCHEMBL7233756 | 0.85 | SIGMAR1 (0.70) | SIGMAR1DRD2OPRL1POLBCCR3 | |
| SCHEMBL7031418 | 0.85 | TSHR (0.62) | SIGMAR1DRD2OPRL1POLBCCR1 | |
| SCHEMBL8096481 | 0.84 | SIGMAR1 (1.00) | SIGMAR1DRD2OPRL1POLBCCR3 | |
| Hydrochloric Acid SCHEMBL11073893 | 0.84 | SIGMAR1 (0.68) | SIGMAR1DRD2OPRL1POLBCCR3 | |
| SCHEMBL14968144 | 0.83 | TSHR (0.64) | SIGMAR1DRD2OPRL1POLBCCR3 | |
| SCHEMBL10697451 | 0.81 | SIGMAR1 (0.65) | SIGMAR1DRD2OPRL1POLBCCR3 | |
| SCHEMBL7104448 | 0.81 | SIGMAR1 (0.65) | SIGMAR1DRD2OPRL1POLBCCR3 | |
| SCHEMBL11717047 | 0.81 | ALDH1A1 (0.74) | SIGMAR1DRD2OPRL1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1273135-C | Pharmaceutical compositions of N-methyl-D-aspartate receptor antagonists | PFIZER PROD INC (US) | 2006-09-06 | — | — | CN | disclosed |
| CN-1479617-A | N-methyl-D-aspartate receptor agonist pharmaceutical compositions | �Ʒ� | 2004-03-03 | — | — | CN | disclosed |
| EP-0584192-A1 | PRODRUG ESTERS OF PHENOLIC 2-PIPERIDINO-1-ALKANOLS | PFIZER INC. (US) | 1994-03-02 | — | — | EP | disclosed |
| EP-0398578-A2 | 2-piperidino-1-alkanol derivatives as antiischemic agents | PFIZER INC. (US) | 1990-11-22 | — | — | EP | disclosed |