Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | SPOP | O43791 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9190737 | 0.88 | KDM4E (0.41) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL9198941 | 0.88 | SPOP (0.41) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL10436335 | 0.87 | KDM4E (0.40) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL10670083 | 0.87 | KDM4E (0.42) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL8077885 | 0.83 | NR1I2 (0.42) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL10582215 | 0.83 | MAPT (0.40) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL8718137 | 0.81 | KDM4E (0.39) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL7636710 | 0.81 | NR1I2 (0.39) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL8882343 | 0.81 | KDM4E (0.39) | KDM4EALDH1A1CYP3A4MAPTAPEX1 | |
| SCHEMBL11470137 | 0.80 | KDM4E (0.40) | KDM4EALDH1A1CYP3A4MAPTAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0256542-A2 | Cephem compounds | Takeda Chemical Industries, Ltd. (JP) | 1988-02-24 | — | — | EP | disclosed |
| EP-0109816-A1 | N-substituted-2-(R)-(sulfinic acid)-3-(S)-(acylamido)-4-oxo-azetidines and process | ELI LILLY AND COMPANY (US) | 1984-05-30 | — | — | EP | disclosed |