Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 3/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.37 |
| ▸ | SPOP | O43791 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8077885 | 0.87 | NR1I2 (0.42) | NR1I2PGRPTGS2TDP1KDM4E | |
| SCHEMBL9388602 | 0.86 | NR1I2 (0.38) | NR1I2PGRPTGS2TDP1KDM4E | |
| SCHEMBL10693978 | 0.86 | NR1I2 (0.39) | NR1I2PGRPTGS2TDP1KDM4E | |
| SCHEMBL10436335 | 0.82 | KDM4E (0.40) | NR1I2PGRPTGS2TDP1KDM4E | |
| SCHEMBL9198941 | 0.81 | SPOP (0.41) | NR1I2PGRPTGS2TDP1KDM4E | |
| SCHEMBL9190737 | 0.81 | KDM4E (0.41) | NR1I2PGRPTGS2TDP1KDM4E | |
| SCHEMBL10670083 | 0.80 | KDM4E (0.42) | NR1I2PGRPTGS2TDP1KDM4E | |
| SCHEMBL10582215 | 0.76 | MAPT (0.40) | NR1I2PGRPTGS2TDP1KDM4E | |
| SCHEMBL9295936 | 0.75 | KDM4E (0.34) | NR1I2PGRPTGS2TDP1KDM4E | |
| SCHEMBL6066202 | 0.75 | NR1I2 (0.42) | NR1I2PGRPTGS2TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230972-A2 | Method of producing cephem compounds | Takeda Chemical Industries, Ltd. (JP) | 1987-08-05 | — | — | EP | claimed |
| US-6458948-B1 | MIXING A QUATERNARY AMMONIUM SALT HAVING A PARTICULAR TRIAZINE RING IN THE MOLECULES THEREOF, A CARBOXYLIC ACID COMPOUND AND A COMPOUND HAVING A NUCLEOPHILIC FUNCTIONAL GROUP, TO CONDENSE THE CARBOXYLIC ACID WITH THE COMPOUND HAVING THE NUCLEOPHILIC | TOKUYAMA CORPORATION (JP) | 2002-10-01 | — | — | US | disclosed |
| EP-0251299-A2 | Cephalosporin compounds, processes for their preparation and antibacterial agents | Kaken Pharmaceutical Co., Ltd. (JP) | 1988-01-07 | — | — | EP | disclosed |
| EP-0091130-A2 | Cephalosporin derivatives, process for preparing and pharmaceutical compositions containing said compounds | DAIICHI SEIYAKU CO., LTD. (JP) | 1983-10-12 | — | — | EP | disclosed |