Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 4/20 | 0.49 |
| ▸ | DRD3 | P35462 | 4/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29671549 | 0.86 | MMP2 (0.47) | MMP2MMP8DRD4DRD3DRD2 | |
| SCHEMBL10699088 | 0.83 | MMP2 (0.52) | MMP2MMP8NPC1MEN1KMT2A | |
| SCHEMBL10697871 | 0.83 | PARP1 (0.43) | NPC1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL10697869 | 0.83 | PARP1 (0.43) | NPC1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL10698628 | 0.83 | ABL1 (0.45) | NPC1MEN1KMT2ARAB9APOLB | |
| SCHEMBL10699522 | 0.81 | ENPP2 (0.46) | NPC1MEN1KMT2ARAB9AMAPT | |
| SCHEMBL10697725 | 0.81 | SMN1; SMN2 (0.43) | NPC1MEN1KMT2ARAB9APOLB | |
| SCHEMBL24435184 | 0.80 | ROCK1 (0.46) | MMP2MMP8DRD4DRD3DRD2 | |
| SCHEMBL10697938 | 0.79 | TYR (0.41) | NPC1MEN1KMT2ARAB9APOLB | |
| SCHEMBL14544155 | 0.78 | NAMPT (0.53) | DRD4DRD3DRD2NAMPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280873-A1 | Piperidines, medicines containing them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-09-07 | — | — | EP | disclosed |