Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3048365 | 0.84 | ALDH1A1 (0.65) | POLBKMT2ALMNATDP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11490589 | 0.80 | KMT2A (0.56) | POLBKMT2ALMNATDP1ALDH1A1 | |
| SCHEMBL17335809 | 0.79 | POLB (0.58) | POLBLMNAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL7280152 | 0.78 | NR4A2 (0.51) | KMT2ALMNATDP1ALDH1A1TSHR | |
| SCHEMBL27597233 | 0.77 | KMT2A (0.82) | KMT2ALMNATDP1ALDH1A1KDM4E | |
| SCHEMBL30335693 | 0.77 | KMT2A (0.82) | KMT2ALMNATDP1ALDH1A1KDM4E | |
| SCHEMBL27891487 | 0.76 | ALDH1A1 (0.58) | POLBKMT2ALMNATDP1ALDH1A1 | |
| SCHEMBL290287 | 0.75 | TDP1 (0.85) | KMT2ALMNATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL786986 | 0.74 | CDC25B (0.61) | POLBKMT2AALDH1A1L3MBTL1KDM4E | |
| SCHEMBL4245622 | 0.74 | KMT2A (0.58) | KMT2ALMNATDP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4734406-A | 3-pyridylmethylnaphthyl derivatives and composition containing them useful to inhibit thromboxane synthetase | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-03-29 | — | — | US | disclosed |