Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695357 | 0.93 | AURKA (0.46) | AURKAAURKBALDH1A1KDM4EHPGD | |
| SCHEMBL10696033 | 0.82 | PDE4A (0.54) | AURKAAURKBALDH1A1KDM4EHPGD | |
| SCHEMBL10699765 | 0.80 | AURKA (0.48) | AURKAAURKBALDH1A1KDM4EHPGD | |
| SCHEMBL13341256 | 0.80 | AURKA (0.49) | AURKAAURKBALDH1A1KDM4EHPGD | |
| SCHEMBL10695470 | 0.79 | MAPT (0.49) | AURKAAURKBALDH1A1KDM4EHPGD | |
| SCHEMBL10694262 | 0.78 | AURKB (0.48) | AURKAAURKB | |
| SCHEMBL4894195 | 0.78 | AURKA (0.50) | AURKAAURKBKDM4E | |
| SCHEMBL13367949 | 0.77 | AURKA (0.47) | AURKAAURKBALDH1A1KDM4ETDP1 | |
| SCHEMBL4510782 | 0.77 | AURKA (0.50) | AURKAAURKBSCD | |
| SCHEMBL10695723 | 0.77 | LMNA (0.44) | AURKAAURKBALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |