SCHEMBL10697013

SCHEMBL10697013

Cc1cc(C2(c3cc(C)c(O)c(C)c3)c3ccccc3-c3ccccc32)ccc1O

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.88
ESR2 Q92731 5/20 0.88
MEN1 O00255 5/20 0.54
KMT2A Q03164 5/20 0.54
LMNA P02545 4/20 0.54
MAPT P10636 4/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
POLB P06746 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
NPSR1 Q6W5P4 2/20 0.54
XBP1 P17861 1/20 0.54
KDM4E B2RXH2 2/20 0.42
OPRK1 P41145 1/20 0.42
ALDH1A1 P00352 2/20 0.40
NPC1 O15118 1/20 0.36
HSP90AA1 P07900 1/20 0.36
RAB9A P51151 1/20 0.36
TP53 P04637 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL70957 0.94 ESR1 (1.00) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL29358768 0.94 ESR1 (1.00) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL29450641 0.94 ESR1 (1.00) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL15691554 0.92 ESR1 (0.97) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL12084149 0.90 ESR1 (0.93) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL515744 0.90 ESR1 (0.69) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL29378579 0.90 ESR1 (0.69) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL30806212 0.90 ESR1 (0.69) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL12387987 0.89 ESR1 (0.90) ESR1ESR2MEN1KMT2ALMNA
SCHEMBL18386002 0.89 ESR1 (0.90) ESR1ESR2MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0274209-A1 Glycidylethers of fluorene-containing bisphenols MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-07-13 EP disclosed
US-4707534-A PROTECTIVE COATINGS, POLYEPOXIDES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-11-17 US disclosed