Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.90 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.90 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450641 | 0.95 | ESR1 (1.00) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL29358768 | 0.95 | ESR1 (1.00) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL70957 | 0.95 | ESR1 (1.00) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL15691554 | 0.93 | ESR1 (0.97) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL12084149 | 0.92 | ESR1 (0.93) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL18348585 | 0.91 | ESR1 (0.80) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL12387987 | 0.90 | ESR1 (0.90) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL6208231 | 0.89 | ESR1 (0.88) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL10697013 | 0.89 | ESR1 (0.88) | ESR1ESR2MEN1KMT2AMAPT | |
| SCHEMBL17399575 | 0.89 | ESR1 (0.88) | ESR1ESR2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170018436-A1 | RESIST UNDERLAYER FILM COMPOSTION, PATTERNING PROCESS, AND COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-01-19 | — | — | US | disclosed |
| US-20170018436-A1 | RESIST UNDERLAYER FILM COMPOSTION, PATTERNING PROCESS, AND COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170018436-A1 | RESIST UNDERLAYER FILM COMPOSTION, PATTERNING PROCESS, AND COMPOUND | PARG, INTS9, FRG1 | ESR1 898/4885ESR2 1340/4885MEN1 2551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.