Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.46 |
| ▸ | S100A10 | P60903 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10700854 | 0.98 | HPGD (0.56) | HPGDCYP2C9CYP2C19CYP3A4MAPK1 | |
| SCHEMBL9557894 | 0.85 | MAPT (0.50) | HPGDCYP2C9CYP2C19MAPK1DHFR | |
| SCHEMBL9814267 | 0.83 | CYP3A4 (0.70) | HPGDCYP2C9CYP2C19CYP3A4MAPK1 | |
| SCHEMBL202221 | 0.83 | CYP3A4 (0.78) | HPGDCYP2C9CYP2C19CYP3A4MAPK1 | |
| SCHEMBL9814281 | 0.81 | CYP3A4 (0.65) | HPGDCYP2C9CYP2C19CYP3A4MAPK1 | |
| Hydrochloric Acid SCHEMBL9230960 | 0.81 | CYP3A4 (0.74) | HPGDCYP2C9CYP2C19CYP3A4MAPK1 | |
| 4,4'-Thiodianiline SCHEMBL28778309 | 0.78 | CYP3A4 (0.88) | HPGDCYP2C9CYP2C19CYP3A4MAPK1 | |
| SCHEMBL3784907 | 0.77 | CYP3A4 (0.67) | HPGDCYP2C9CYP2C19CYP3A4MAPK1 | |
| SCHEMBL9625758 | 0.76 | CYP2C9 (0.54) | HPGDCYP2C9CYP2C19MAPK1TSHR | |
| Diphenylsulfane SCHEMBL27459834 | 0.76 | TSHR (0.65) | HPGDCYP2C9CYP2C19CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268091-A1 | Crystalline polyimides containing cumulative phenylene sulfide units | GENERAL ELECTRIC COMPANY (US) | 1988-05-25 | — | — | EP | claimed |