Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | PDE7A | Q13946 | 5/20 | 0.54 |
| ▸ | DHFR | P00374 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.42 |
| ▸ | S100A10 | P60903 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814267 | 0.97 | CYP3A4 (0.70) | CYP3A4TSHRMAPK1HPGDCYP2C9 | |
| SCHEMBL3095695 | 0.88 | CYP3A4 (0.56) | CYP3A4TSHRMAPK1HPGDCYP2C9 | |
| SCHEMBL18620896 | 0.84 | CYP3A4 (0.52) | CYP3A4TSHRMAPK1HPGDCYP2C9 | |
| SCHEMBL10616298 | 0.84 | HPGD (0.53) | CYP3A4TSHRMAPK1HPGDCYP2C9 | |
| SCHEMBL10700854 | 0.83 | HPGD (0.56) | CYP3A4TSHRMAPK1HPGDCYP2C9 | |
| SCHEMBL202221 | 0.81 | CYP3A4 (0.78) | CYP3A4TSHRMAPK1HPGDCYP2C9 | |
| SCHEMBL10697015 | 0.81 | HPGD (0.54) | CYP3A4TSHRMAPK1HPGDCYP2C9 | |
| SCHEMBL8558465 | 0.81 | KDM1A (0.51) | CYP3A4TSHRMAPK1HPGDCYP2C9 | |
| SCHEMBL3897205 | 0.80 | SIRT1 (0.52) | MAPK1HPGDCYP2C9CYP2C19DHFR | |
| 4,4'-Thiodianiline SCHEMBL28778309 | 0.80 | CYP3A4 (0.88) | CYP3A4TSHRMAPK1HPGDCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0260709-B1 | FUSIBLE AND SOLUBLE POLYAMIDEIMIDE-POLYIMIDE BLOCK POLYMERS | Chemie Linz Gesellschaft m.b.H. (AT) | 1991-07-24 | — | — | EP | disclosed |
| EP-0294848-A1 | Aromatic polythioetherimide | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1988-12-14 | — | — | EP | disclosed |
| EP-0260709-A1 | Fusible and soluble polyamideimide-polyimide block polymers | Chemie Linz Gesellschaft m.b.H. (AT) | 1988-03-23 | — | — | EP | disclosed |