Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.50 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.48 |
| ▸ | S100A10 | P60903 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4985310 | 0.95 | CYP3A4 (0.71) | CYP3A4TSHRMAPK1TDP1HSD17B10 | |
| SCHEMBL202221 | 0.93 | CYP3A4 (0.78) | CYP3A4TSHRMAPK1TDP1HSD17B10 | |
| Hydrochloric Acid SCHEMBL9230960 | 0.90 | CYP3A4 (0.74) | CYP3A4TSHRMAPK1TDP1HSD17B10 | |
| SCHEMBL9153502 | 0.90 | CYP3A4 (0.82) | CYP3A4TSHRMAPK1TDP1HSD17B10 | |
| SCHEMBL9647851 | 0.90 | CYP3A4 (0.82) | CYP3A4TSHRMAPK1TDP1HSD17B10 | |
| SCHEMBL1270077 | 0.90 | CYP3A4 (0.82) | CYP3A4TSHRMAPK1TDP1HSD17B10 | |
| SCHEMBL9485845 | 0.90 | CYP3A4 (0.82) | CYP3A4TSHRMAPK1TDP1HSD17B10 | |
| SCHEMBL29177683 | 0.88 | CYP3A4 (0.61) | CYP3A4TSHRMAPK1TDP1HSD17B10 | |
| 4,4'-Thiodianiline SCHEMBL28778309 | 0.87 | CYP3A4 (0.88) | CYP3A4TSHRMAPK1TDP1HSD17B10 | |
| SCHEMBL2754909 | 0.87 | MAOA (0.54) | CYP3A4TSHRMAPK1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | CYP3A4 177/4885TSHR 1688/4885MAPK1 4726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.