Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | PPOX | P50336 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 14/20 | 0.39 |
| ▸ | GABRD | O14764 | 14/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 14/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 14/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 14/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697700 | 0.84 | TDP1 (0.47) | TDP1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL10698683 | 0.82 | TDP1 (0.44) | TDP1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL10695727 | 0.82 | TDP1 (0.42) | TDP1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL10697624 | 0.81 | S1PR4 (0.44) | TDP1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL20476784 | 0.79 | TXNRD1 (0.57) | TXNRD1MAPTNPSR1 | |
| SCHEMBL20471448 | 0.78 | CYP3A4 (0.39) | TDP1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL10697848 | 0.78 | FGFR4 (0.45) | TDP1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL11650906 | 0.78 | TDP1 (0.49) | TDP1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL10697235 | 0.78 | TDP1 (0.41) | TDP1ALDH1A1CYP3A4HPGDALOX15 | |
| SCHEMBL10698436 | 0.78 | MEN1 (0.43) | TDP1ALDH1A1CYP3A4HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |