Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.44 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.44 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | PPOX | P50336 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696869 | 0.93 | TDP1 (0.41) | TDP1CYP3A4ALDH1A1HPGDALOX15 | |
| SCHEMBL10697700 | 0.88 | TDP1 (0.47) | TDP1CYP3A4ALDH1A1HPGDALOX15 | |
| SCHEMBL10990765 | 0.86 | TDP1 (0.55) | TDP1CYP3A4ALDH1A1HPGDALOX15 | |
| SCHEMBL10698177 | 0.85 | TDP1 (0.36) | TDP1CYP3A4ALDH1A1HPGDALOX15 | |
| SCHEMBL10696364 | 0.84 | EPAS1 (0.36) | TDP1CYP3A4ALDH1A1HPGDALOX15 | |
| SCHEMBL10695727 | 0.82 | TDP1 (0.42) | TDP1CYP3A4ALDH1A1HPGDALOX15 | |
| SCHEMBL10697029 | 0.82 | TDP1 (0.42) | TDP1CYP3A4ALDH1A1HPGDALOX15 | |
| SCHEMBL10697624 | 0.81 | S1PR4 (0.44) | TDP1CYP3A4ALDH1A1HPGDALOX15 | |
| SCHEMBL20476784 | 0.80 | TXNRD1 (0.57) | TXNRD1MAPTNPSR1 | |
| SCHEMBL20471448 | 0.79 | CYP3A4 (0.39) | TDP1CYP3A4ALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |