Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10357275 | 0.90 | SMN1; SMN2 (0.34) | TSHRMEN1KMT2ASMN1; SMN2NOTUM | |
| SCHEMBL1322693 | 0.80 | NOTUM (0.36) | TSHRSMN1; SMN2NOTUM | |
| SCHEMBL10357220 | 0.80 | TSHR (0.31) | TSHRSMN1; SMN2NOTUM | |
| SCHEMBL26618446 | 0.78 | TSHR (0.50) | TSHRHPGDHSD17B10MEN1ALDH1A1 | |
| SCHEMBL7069317 | 0.76 | TSHR (0.33) | TSHRSMN1; SMN2NOTUM | |
| SCHEMBL28517192 | 0.75 | NOTUM (0.36) | TSHRMEN1KMT2ASMN1; SMN2NOTUM | |
| SCHEMBL186352 | 0.75 | SMN1; SMN2 (0.40) | TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9747850 | 0.74 | NOTUM (0.33) | NOTUM | |
| SCHEMBL28781590 | 0.74 | NOTUM (0.32) | NOTUM | |
| SCHEMBL9244075 | 0.74 | NOTUM (0.33) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272533-A2 | Substituted phenoxypyridines | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |