SCHEMBL186352

SCHEMBL186352

Oc1c(F)c(F)c(C(F)(F)F)c(F)c1F

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.40
TSHR P16473 1/20 0.40
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26948675 0.94 SMN1; SMN2 (0.38) SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL14062570 0.85 TSHR (0.30) SMN1; SMN2TSHR
SCHEMBL20548535 0.85 SMN1; SMN2 (0.34) SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL312355 0.83 SMN1; SMN2 (0.42) SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL10357275 0.82 SMN1; SMN2 (0.34) SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL29030085 0.82 SMN1; SMN2 (0.34) SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL26948692 0.82 SMN1; SMN2 (0.34) SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL7917304 0.81
SCHEMBL14063423 0.81 TSHR (0.31) SMN1; SMN2TSHR
Perfluorotoluene SCHEMBL308464 0.79 SMN1; SMN2 (0.41) SMN1; SMN2TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 252 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119431706-A Fatigue-resistant polyurethane elastomer and preparation method and application thereof 万勋科技(深圳)有限公司 2025-02-14 CN claimed
CN-118084634-A Preparation method of fluorine-containing ether and fluorine-containing ether 纯钧新材料(深圳)有限公司 2024-05-28 CN claimed
US-9815809-B2 Formation of chiral 4-chromanones using chiral pyrrolidines in the presence of phenols or thiophenols DSM IP ASSETS B.V. (NL) 2017-11-14 US claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 US claimed
US-4960539-A Use of fluoromethylphenols as solvents for LC-polymers, and new fluoromethylphenols BAYER AKTIENGESELLSCHAFT (DE) 1990-10-02 US claimed
US-12577373-B2 Carbodiimide composition, curing agent composition, coating composition and resin cured product ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-03-17 US disclosed
WO-2025070077-A1 CURABLE RESIN COMPOSITION, CURED ARTICLE, AND OPTICAL WAVEGUIDE DIC株式会社 2025-04-03 WO disclosed
CN-119431706-A Fatigue-resistant polyurethane elastomer and preparation method and application thereof 万勋科技(深圳)有限公司 2025-02-14 CN disclosed
US-20240231222-A1 PHOTORESIST COMPOSITION AND METHOD OF FABRICATING SEMICONDUCTOR DEVICE SAMSUNG ELECTRONICS CO., LTD. (KR) 2024-07-11 US disclosed
US-12029120-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-07-02 US disclosed
CN-118084634-A Preparation method of fluorine-containing ether and fluorine-containing ether 纯钧新材料(深圳)有限公司 2024-05-28 CN disclosed
US-20240155942-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2024-05-09 US disclosed
US-5604213-A STEROID DEPENDENT CANCERS SUCH AS PROSTATE AND BREAST CANCER BRITISH TECHNOLOGY GROUP LIMITED (GB) 1997-02-18 US disclosed
EP-0633893-A1 17-SUBSTITUTED STEROIDS USEFUL IN CANCER TREATMENT BRITISH TECHNOLOGY GROUP LTD (GB) 1995-01-18 EP disclosed
WO-1993020097-A1 17-SUBSTITUTED STEROIDS USEFUL IN CANCER TREATMENT BRITISH TECHNOLOGY GROUP LTD. (GB) 1993-10-14 WO disclosed
US-4960539-A Use of fluoromethylphenols as solvents for LC-polymers, and new fluoromethylphenols BAYER AKTIENGESELLSCHAFT (DE) 1990-10-02 US disclosed
EP-0286953-B1 USE OF FLUOROMETHYL PHENOLS AS SOLVENTS FOR LC POLYMERS, AND FLUOROMETHYL PHENOLS BAYER AG (DE) 1990-09-26 EP disclosed
EP-0286953-A1 Use of fluoromethyl phenols as solvents for LC polymers, and fluoromethyl phenols BAYER AG (DE) 1988-10-19 EP disclosed
EP-0272533-A2 Substituted phenoxypyridines BAYER AG (DE) 1988-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577373-B2 Carbodiimide composition, curing agent composition, coating composition and resin cured product CD38, PARP9, MCCC2 SMN1; SMN2 1368/4885TSHR 4705/4885MEN1 3653/4885
US-12029120-B2 Organic electroluminescence element and electronic device RPS10, H1-10, OR10J3 SMN1; SMN2 3913/4885TSHR 3535/4885MEN1 1431/4885
US-20240155942-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE RPS10, H1-10, OR10J3 SMN1; SMN2 3913/4885TSHR 3535/4885MEN1 1431/4885
US-20240231222-A1 PHOTORESIST COMPOSITION AND METHOD OF FABRICATING SEMICONDUCTOR DEVICE ZKSCAN2, PIN1, CRY1 SMN1; SMN2 3748/4885TSHR 2085/4885MEN1 1073/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.