Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10696478 | 0.98 | PBRM1 (0.51) | PBRM1ATMTDP1L3MBTL1MAPK1 | |
| SCHEMBL11460048 | 0.86 | SRD5A2 (0.49) | TDP1MAPK1ALDH1A1MAPTPOLB | |
| SCHEMBL11461769 | 0.82 | ALDH1A1 (0.51) | L3MBTL1MAPK1ALDH1A1MAPTPTGS1 | |
| SCHEMBL11460323 | 0.82 | SRD5A2 (0.59) | ALDH1A1MAPTPTGS1LMNAADORA1 | |
| SCHEMBL11462459 | 0.81 | SRD5A2 (0.54) | ALDH1A1POLBSRD5A2 | |
| SCHEMBL11462372 | 0.81 | ALDH1A1 (0.47) | TDP1MAPK1ALDH1A1MAPTPOLB | |
| SCHEMBL10704144 | 0.80 | AKR1B1 (0.58) | PBRM1ATMTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL7287427 | 0.79 | PBRM1 (0.45) | PBRM1ATMTDP1L3MBTL1MAPK1 | |
| SCHEMBL7487247 | 0.79 | ATM (0.50) | ATMTDP1L3MBTL1ALDH1A1POLB | |
| SCHEMBL11461163 | 0.78 | SRD5A2 (0.60) | MAPK1ALDH1A1MAPTSRD5A2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255178-A2 | Process for preparing hetero aryl and aryl alkanoic acids | Nobel Chemicals AB (SE) | 1988-02-03 | — | — | EP | disclosed |