Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | ELANE | P08246 | 3/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7489481 | 0.87 | ATM (0.47) | ATMTDP1L3MBTL1ALDH1A1ELANE | |
| SCHEMBL13760153 | 0.86 | PTGS1 (0.54) | ATMTDP1L3MBTL1ALDH1A1ELANE | |
| SCHEMBL20612873 | 0.84 | ALDH1A1 (0.46) | TDP1L3MBTL1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL7490444 | 0.83 | L3MBTL1 (0.43) | ATMTDP1L3MBTL1ALDH1A1ELANE | |
| SCHEMBL2382916 | 0.82 | MRGPRX4 (0.49) | TDP1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL10704144 | 0.81 | AKR1B1 (0.58) | ATMTDP1L3MBTL1ALDH1A1ELANE | |
| SCHEMBL10696478 | 0.80 | PBRM1 (0.51) | ATMTDP1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10703272 | 0.80 | CYP1A2 (0.61) | ATML3MBTL1ALDH1A1ELANEHTT | |
| Methane SCHEMBL10697071 | 0.79 | PBRM1 (0.50) | ATMTDP1L3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL166495 | 0.78 | SMN1; SMN2 (0.71) | ATMTDP1L3MBTL1ALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1201661-A1 | HETEROAROMATIC RING COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2002-05-02 | — | — | EP | disclosed |