Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2697405 | 0.98 | MTNR1A (0.45) | MTNR1ASMYD3MAPTGAANPC1 | |
| SCHEMBL13305784 | 0.98 | MTNR1A (0.45) | MTNR1ASMYD3MAPTGAANPC1 | |
| SCHEMBL28901934 | 0.86 | MAPT (0.43) | MTNR1ASMYD3MAPTGAANPC1 | |
| SCHEMBL19774297 | 0.77 | MTNR1A (0.47) | MTNR1ASMYD3MAPTGAANPC1 | |
| SCHEMBL2781001 | 0.77 | MAPT (0.55) | MTNR1AMAPTGAANPC1KDM4E | |
| SCHEMBL31517110 | 0.77 | MAPT (0.55) | MTNR1AMAPTGAANPC1KDM4E | |
| SCHEMBL28043088 | 0.76 | MTNR1A (0.47) | MTNR1ASMYD3MAPTGAANPC1 | |
| SCHEMBL20344534 | 0.76 | ANPEP (0.50) | MTNR1ASMYD3MAPTGAANPC1 | |
| Hydrochloric Acid SCHEMBL27277923 | 0.75 | GAA (0.53) | MTNR1AMAPTGAAANPEP | |
| SCHEMBL19088009 | 0.74 | ESR2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1017435-B | PROCESS FOR PREPARATION OF GLYCEROL DERIVATIVES | NIPPON CHEMIPHAR CO (JP) | 1992-07-15 | — | — | CN | disclosed |
| CN-1030239-A | The preparation method of new glycerol derivative | NIPPON CHEMIPHAR CO (JP) | 1989-01-11 | — | — | CN | disclosed |
| EP-0284395-A2 | Novel glycerol derivative and anti-hypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1988-09-28 | — | — | EP | disclosed |