Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 5/20 | 0.47 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726820 | 0.79 | ESR2 (0.46) | ESR2ESR1DRD2DRD3OPRK1 | |
| SCHEMBL13091390 | 0.79 | DRD2 (0.39) | ESR2ESR1DRD2 | |
| SCHEMBL2697405 | 0.76 | MTNR1A (0.45) | — | |
| SCHEMBL13305784 | 0.76 | MTNR1A (0.45) | — | |
| SCHEMBL21465771 | 0.75 | GAA (0.44) | ESR2ESR1DRD2DRD3OPRK1 | |
| Methane SCHEMBL10697109 | 0.74 | MTNR1A (0.44) | — | |
| SCHEMBL14409327 | 0.72 | ESR2 (0.50) | ESR2ESR1DRD2DRD3OPRK1 | |
| SCHEMBL5234926 | 0.72 | ESR2 (0.50) | ESR2ESR1DRD2DRD3OPRK1 | |
| SCHEMBL5235986 | 0.72 | ESR2 (0.50) | ESR2ESR1DRD2DRD3OPRK1 | |
| SCHEMBL5235983 | 0.72 | ESR2 (0.50) | ESR2ESR1DRD2DRD3OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397636-B1 | PROCESS FOR THE PREPARATION OF QUINOLINE-2(1H)-ONE DERIVATIVES | HONOUR R&D (IN) | 2021-08-04 | — | — | EP | disclosed |
| WO-2017115287-A1 | PROCESS FOR THE PREPARATION OF QUINOLINE-2(1H)-ONE DERIVATIVES | HONOUR (R&D) (IN) | 2017-07-06 | — | — | WO | disclosed |