Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.40 |
| ▸ | F13A1 | P00488 | 3/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3402945 | 0.82 | TDP1 (0.51) | MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9424812 | 0.79 | PARP1 (0.46) | MEN1KMT2APARP1PARP2 | |
| SCHEMBL6274670 | 0.76 | MAPT (0.51) | MAPTRXFP1MEN1KMT2ALTB4R | |
| SCHEMBL31536704 | 0.76 | MAPT (0.51) | MAPTRXFP1MEN1KMT2ALTB4R | |
| SCHEMBL29078299 | 0.76 | BID (0.53) | MAPTTLR8ALOX15 | |
| SCHEMBL7105692 | 0.76 | KMT2A (0.50) | MAPTRXFP1MEN1KMT2ATLR8 | |
| SCHEMBL6673816 | 0.75 | RXFP1 (0.44) | MAPTRXFP1MEN1KMT2ATLR8 | |
| SCHEMBL1616841 | 0.74 | TDP1 (0.59) | MAPTRXFP1MEN1KMT2AF13A1 | |
| SCHEMBL3732554 | 0.74 | TDP1 (0.59) | MAPTRXFP1MEN1KMT2AF13A1 | |
| SCHEMBL710750 | 0.74 | TDP1 (0.59) | MAPTRXFP1MEN1KMT2AF13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273115-A2 | Chemiluminescent acridinium and phenanthridinium salts | ABBOTT LABORATORIES (US) | 1988-07-06 | — | — | EP | disclosed |