Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 18/20 | 0.64 |
| ▸ | ADRB3 | P13945 | 16/20 | 0.64 |
| ▸ | DRD2 | P14416 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.64 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.64 |
| ▸ | DRD4 | P21917 | 1/20 | 0.64 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | FPR3 | P25089 | 1/20 | 0.64 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.64 |
| ▸ | HTR1D | P28221 | 1/20 | 0.64 |
| ▸ | HTR1B | P28222 | 1/20 | 0.64 |
| ▸ | HTR2A | P28223 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29751132 | 0.96 | ADRB2 (0.70) | ADRB2ADRB1ADRB3DRD2KDM4E | |
| SCHEMBL461364 | 0.96 | ADRB2 (0.70) | ADRB2ADRB1ADRB3DRD2KDM4E | |
| SCHEMBL9864677 | 0.94 | ADRB2 (0.67) | ADRB2ADRB1ADRB3DRD2KDM4E | |
| SCHEMBL5008664 | 0.86 | ADRB2 (0.60) | ADRB2ADRB1ADRB3DRD2KDM4E | |
| Carboxynaphthol SCHEMBL462270 | 0.83 | ADRB2 (0.78) | ADRB2ADRB1ADRB3DRD2KDM4E | |
| SCHEMBL10701369 | 0.82 | ADRB2 (0.53) | ADRB2ADRB1ADRB3DRD2KDM4E | |
| SCHEMBL10700013 | 0.82 | ADRB2 (0.92) | ADRB2ADRB1ADRB3DRD2KDM4E | |
| SCHEMBL10338191 | 0.82 | ADRB2 (0.52) | ADRB2ADRB1ADRB3DRD2KDM4E | |
| SCHEMBL10514014 | 0.81 | ADRB2 (0.52) | ADRB2ADRB1ADRB3DRD2KDM4E | |
| SCHEMBL10513403 | 0.80 | ADRB2 (0.50) | ADRB2ADRB1ADRB3DRD2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0286242-A2 | Ethanolamine derivates, processes for their preparation and pharmaceutical compositions containing them | GLAXO GROUP LIMITED (GB) | 1988-10-12 | — | — | EP | claimed |