Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 16/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 13/20 | 0.60 |
| ▸ | ADRB3 | P13945 | 12/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.60 |
| ▸ | DRD3 | P35462 | 2/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | HTR1A | P08908 | 1/20 | 0.60 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL461364 | 0.91 | ADRB2 (0.70) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL29751132 | 0.91 | ADRB2 (0.70) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL9864677 | 0.88 | ADRB2 (0.67) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL10697205 | 0.86 | ADRB2 (0.64) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL5008661 | 0.80 | ADRB2 (0.52) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| Carboxynaphthol SCHEMBL462270 | 0.78 | ADRB2 (0.78) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL10701369 | 0.78 | ADRB2 (0.53) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL5008719 | 0.78 | ADRB2 (0.46) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL23048394 | 0.77 | ADRB2 (0.69) | ADRB2ADRB1ADRB3KDM4EMEN1 | |
| SCHEMBL10338191 | 0.77 | ADRB2 (0.52) | ADRB2ADRB1ADRB3KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937626-B1 | Process and intermediates for the preparation of Salmeterol | GENERICS UK LTD (GB) | 2016-02-17 | — | — | EP | disclosed |
| US-8648214-B2 | Processes suitable for the preparation of salmeterol | GENERICS [UK] LIMITED (GB) | 2014-02-11 | — | — | US | disclosed |
| EP-2641893-A1 | PROCESS FOR THE PREPARATION OF SALMETEROL AND ITS SALTS | Generics [UK] Limited (GB) | 2013-09-25 | — | — | EP | disclosed |
| US-20080262267-A1 | NOVEL PROCESS | GENERICS [UK] LIMITED (GB) | 2008-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262267-A1 | NOVEL PROCESS | CYP4A11, HSD3B1, HSD11B1 | ADRB2 128/4885ADRB1 53/4885ADRB3 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.