SCHEMBL1069721

SCHEMBL1069721

CN(C)C(On1nnc2ccc(Cl)cc21)=[N+](C)C.F[B-](F)(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 2/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ ALDH1A1 P00352 3/20 0.38
▸ HPGD P15428 3/20 0.38
▸ SMN1; SMN2 Q16637 3/20 0.37
▸ POLB P06746 1/20 0.36
▸ KMO O15229 1/20 0.36
▸ HDAC3 O15379 4/20 0.36
▸ HDAC4 P56524 4/20 0.36
▸ HDAC1 Q13547 4/20 0.36
▸ HDAC7 Q8WUI4 4/20 0.36
▸ HDAC2 Q92769 4/20 0.36
▸ HDAC10 Q969S8 4/20 0.36
▸ HDAC11 Q96DB2 4/20 0.36
▸ HDAC8 Q9BY41 4/20 0.36
▸ HDAC6 Q9UBN7 4/20 0.36
▸ HDAC9 Q9UKV0 4/20 0.36
▸ HDAC5 Q9UQL6 4/20 0.36
▸ NPC1 O15118 3/20 0.35
▸ RAB9A P51151 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29467313 1.00 KMT2A (0.40) KMT2AMEN1ALDH1A1HPGDSMN1; SMN2
SCHEMBL15771522 1.00 KMT2A (0.40) KMT2AMEN1ALDH1A1HPGDSMN1; SMN2
SCHEMBL526205 0.95 KMT2A (0.41) KMT2AMEN1ALDH1A1HPGDSMN1; SMN2
SCHEMBL29551956 0.95 KMT2A (0.41) KMT2AMEN1ALDH1A1HPGDSMN1; SMN2
SCHEMBL19894763 0.93 KMT2A (0.40) KMT2AMEN1ALDH1A1HPGDSMN1; SMN2
SCHEMBL15771526 0.93 KMT2A (0.40) KMT2AMEN1ALDH1A1HPGDSMN1; SMN2
SCHEMBL16322925 0.93 KMT2A (0.40) KMT2AMEN1ALDH1A1HPGDSMN1; SMN2
SCHEMBL29350952 0.93 KMT2A (0.40) KMT2AMEN1ALDH1A1HPGDSMN1; SMN2
Fluoride Ion SCHEMBL29715858 0.92 KMT2A (0.40) KMT2AMEN1ALDH1A1HPGDSMN1; SMN2
SCHEMBL2367518 0.91 KMT2A (0.39) KMT2AMEN1ALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 695 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 — — US claimed
US-12508321-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-12-30 — — US claimed
US-12496351-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers HANGZHOU DAC BIOTECH CO., LTD. (CN) 2025-12-16 — — US claimed
US-20250320251-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING NOVEL CYCLIC PEPTIDES LISATA THERAPEUTICS INC (US) 2025-10-16 — — US claimed
WO-2025119223-A1 METHOD FOR SYNTHESIZING AMANITIN AND DERIVATIVE THEREOF 上海皓元生物医药科技有限公司 2025-06-12 — — WO claimed
WO-2025094036-A1 A PROCESS FOR THE PREPARATION OF LIRAGLUTIDE PIRAMAL PHARMA LIMITED (IN) 2025-05-08 — — WO claimed
US-20250109170-A1 METHOD FOR MANUFACTURING GANIRELIX ANYGEN CO., LTD. (KR) 2025-04-03 — — US claimed
EP-4190786-B1 COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE VERTEX PHARMA (US) 2025-02-26 — — EP claimed
US-20250002531-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES STEALTH BIOTHERAPEUTICS INC. (US) 2025-01-02 — — US claimed
EP-4472948-A2 NICOTINATE AND NICOTINAMIDE RIBOSIDE-BASED COMPOUNDS AND DERIVATIVES THEREOF New Frontier Bio, Inc. (US) 2024-12-11 — — EP claimed
US-10292961-B2 Disulfur bridge linkers for conjugation of a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD. (CN) 2019-05-21 — — US claimed
US-10293055-B2 Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD. (CN) 2019-05-21 — — US claimed
US-10232051-B2 Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD. (CN) 2019-03-19 — — US claimed
US-10221213-B2 Pharmaceutically relevant aromatic-cationic peptides STEALTH BIOTHERAPEUTICS CORP (MC) 2019-03-05 — — US claimed
EP-3411074-A2 SPECIFIC CONJUGATION LINKERS, SPECIFIC IMMUNOCONJUGATES THEREOF, METHODS OF MAKING AND USES SUCH CONJUGATES THEREOF Suzhou M-conj Biotech Co., Ltd. (CN) 2018-12-12 — — EP claimed
WO-2018185526-A1 CONJUGATION OF A CYTOTOXIC DRUG WITH BIS-LINKAGE HANGZHOU DAC BIOTECH CO., LTD (CN) 2018-10-11 — — WO claimed
US-9839687-B2 Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule SUZHOU M-CONJ BIOTECH CO., LTD. (CN) 2017-12-12 — — US claimed
US-20170081363-A1 PHARMACEUTICALLY RELEVANT AROMATIC-CATIONIC PEPTIDES STEALTH BIOTHERAPEUTICS CORP (MC) 2017-03-23 — — US claimed
US-20160340389-A1 PHARMACEUTICALLY RELEVANT AROMATIC-CATIONIC PEPTIDES STEALTH BIOTHERAPEUTICS INC. 2016-11-24 — — US claimed
US-20150322155-A1 ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE Sushou M-conj Biotech Co., Ltd (CN) 2015-11-12 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160340389-A1 PHARMACEUTICALLY RELEVANT AROMATIC-CATIONIC PEPTIDES ADM2, VIP, ANPEP KMT2A 694/4885MEN1 433/4885ALDH1A1 4716/4885
US-10292961-B2 Disulfur bridge linkers for conjugation of a cell-binding molecule CD74, CD2, EPCAM KMT2A 2757/4885MEN1 1221/4885ALDH1A1 900/4885
US-12508321-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers CD4, CD2, B2M KMT2A 1887/4885MEN1 780/4885ALDH1A1 2817/4885
US-10221213-B2 Pharmaceutically relevant aromatic-cationic peptides ADM2, VIP, ANPEP KMT2A 694/4885MEN1 433/4885ALDH1A1 4716/4885
US-20170081363-A1 PHARMACEUTICALLY RELEVANT AROMATIC-CATIONIC PEPTIDES ADM2, VIP, ANPEP KMT2A 503/4885MEN1 504/4885ALDH1A1 4618/4885
US-20250002531-A1 PROCESSES FOR PREPARING PHARMACEUTICALLY RELEVANT PEPTIDES ADM2, VIP, PEPD KMT2A 767/4885MEN1 194/4885ALDH1A1 4638/4885
US-20250320251-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING NOVEL CYCLIC PEPTIDES VIP, NGLY1, GRPR KMT2A 4802/4885MEN1 398/4885ALDH1A1 4774/4885
US-10293055-B2 Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule AADAC, EPCAM, DCLRE1A KMT2A 3337/4885MEN1 2819/4885ALDH1A1 429/4885
US-12496351-B2 Conjugation linkers, cell binding molecule-drug conjugates containing the linkers, methods of making and uses such conjugates with the linkers CD2BP2, DCLRE1A, EPCAM KMT2A 3090/4885MEN1 2291/4885ALDH1A1 618/4885
US-20250109170-A1 METHOD FOR MANUFACTURING GANIRELIX VIP, GLP1R, CCKBR KMT2A 4309/4885MEN1 1642/4885ALDH1A1 3518/4885
US-20150322155-A1 ACETYLENEDICARBOXYL LINKERS AND THEIR USES IN SPECIFIC CONJUGATION OF A CELL-BINDING MOLECULE DCLRE1A, AADAC, UACA KMT2A 2220/4885MEN1 1621/4885ALDH1A1 952/4885
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS DCLRE1A, CCR3, CCR8 KMT2A 3633/4885MEN1 2393/4885ALDH1A1 2641/4885
US-10232051-B2 Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule AADAC, EPCAM, DCLRE1A KMT2A 3337/4885MEN1 2819/4885ALDH1A1 429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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