Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 11/20 | 0.67 |
| ▸ | SHBG | P04278 | 1/20 | 0.57 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2163618 | 0.82 | SHBG (0.68) | STSSHBGHSD17B1ESR1LMNA | |
| SCHEMBL3974914 | 0.77 | STS (0.65) | STSSHBGHSD17B1ESR1LMNA | |
| SCHEMBL11861023 | 0.76 | LMNA (0.55) | STSSHBGHSD17B1ESR1LMNA | |
| SCHEMBL14364736 | 0.76 | STS (0.61) | STSSHBGHSD17B1ESR1LMNA | |
| SCHEMBL5525154 | 0.76 | STS (0.61) | STSSHBGHSD17B1ESR1LMNA | |
| SCHEMBL9242677 | 0.75 | SHBG (0.58) | STSSHBGHSD17B1ESR1LMNA | |
| SCHEMBL8424316 | 0.74 | STS (0.89) | STSESR1LMNA | |
| SCHEMBL712443 | 0.73 | SHBG (1.00) | STSSHBGHSD17B1ESR1LMNA | |
| SCHEMBL29643366 | 0.73 | SHBG (1.00) | STSSHBGHSD17B1ESR1LMNA | |
| SCHEMBL172746 | 0.73 | SHBG (1.00) | STSSHBGHSD17B1ESR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280618-A1 | 19-Nor steroids substituted at position 7, their preparation, their use as medicaments and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1988-08-31 | — | — | EP | disclosed |