Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16168058 | 0.80 | MEN1 (0.56) | KMT2AMEN1SRCCYP2D6HPGD | |
| SCHEMBL9172139 | 0.74 | TRPM8 (0.44) | KMT2ACYP2D6HPGDLMNACES2 | |
| SCHEMBL11429072 | 0.74 | L3MBTL1 (0.52) | KMT2AMEN1LMNAMAPK1CES2 | |
| Benzene SCHEMBL27414119 | 0.73 | L3MBTL1 (0.56) | KMT2ASRCCYP2D6HPGDLMNA | |
| SCHEMBL5608251 | 0.73 | CYP2D6 (0.64) | MTNR1AMTNR1BKMT2ASRCCYP2D6 | |
| SCHEMBL1312762 | 0.73 | SRC (0.64) | MTNR1AMTNR1BKMT2ASRCCYP2D6 | |
| SCHEMBL396389 | 0.73 | L3MBTL1 (0.56) | KMT2ASRCCYP2D6HPGDLMNA | |
| SCHEMBL10974191 | 0.72 | TRPM8 (0.50) | ALOX5 | |
| SCHEMBL13389739 | 0.72 | CHRM2 (0.46) | KMT2AMEN1SRCCYP2D6HPGD | |
| SCHEMBL5423153 | 0.72 | DPP4 (0.45) | SRCCYP2D6LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0264744-A2 | Process for the preparation of 4,4'-diaminodiphenylmethane and its derivatives | ENIRICERCHE S.p.A. (IT) | 1988-04-27 | — | — | EP | disclosed |