Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4754819 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MAPTCYP3A4TSHRLOXL2 | |
| SCHEMBL6690598 | 0.84 | LOXL2 (0.52) | ALDH1A1MAPTCYP1A2CYP3A4TSHR | |
| Ammonia Solution, Strong SCHEMBL4821086 | 0.83 | ALDH1A1 (0.45) | ALDH1A1MAPTCYP1A2CYP3A4TSHR | |
| SCHEMBL27520363 | 0.81 | GRM8 (0.44) | ALDH1A1MAPTCYP1A2CYP3A4TSHR | |
| SCHEMBL16805961 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MAPTCYP1A2CYP3A4TSHR | |
| SCHEMBL43298 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPTCYP1A2CYP3A4TSHR | |
| SCHEMBL894479 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPTCYP1A2CYP3A4TSHR | |
| SCHEMBL895913 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPTCYP1A2CYP3A4TSHR | |
| SCHEMBL18833848 | 0.78 | LOXL2 (0.53) | ALDH1A1MAPTCYP1A2CYP3A4TSHR | |
| SCHEMBL942066 | 0.78 | LOXL2 (0.53) | ALDH1A1MAPTCYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0275101-A2 | Novel peptidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-07-20 | — | — | EP | disclosed |