Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.53 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 4/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6563037 | 0.91 | LOXL2 (0.50) | LOXL2MC4RDPP4DPP7IDO1 | |
| SCHEMBL8829959 | 0.88 | LOXL2 (0.47) | LOXL2MC4RDPP4DPP7IDO1 | |
| SCHEMBL514488 | 0.83 | LOXL2 (0.60) | LOXL2MC4RDPP4DPP7IDO1 | |
| SCHEMBL5148823 | 0.83 | LOXL2 (0.60) | LOXL2MC4RDPP4DPP7IDO1 | |
| SCHEMBL22179659 | 0.82 | LOXL2 (0.50) | LOXL2DPP4DPP7IDO1ANPEP | |
| Hydrochloric Acid SCHEMBL9355954 | 0.81 | LOXL2 (0.58) | LOXL2MC4RDPP4DPP7IDO1 | |
| SCHEMBL12793699 | 0.81 | CHRM2 (0.49) | LOXL2MC4RDPP4DPP7IDO1 | |
| SCHEMBL6523856 | 0.80 | LOXL2 (0.49) | LOXL2MC4RDPP4DPP7IDO1 | |
| SCHEMBL4092879 | 0.80 | LOXL2 (0.49) | LOXL2MC4RDPP4DPP7IDO1 | |
| SCHEMBL4104161 | 0.80 | LOXL2 (0.49) | LOXL2MC4RDPP4DPP7IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0275101-A2 | Novel peptidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-07-20 | — | — | EP | disclosed |