Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 4/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697391 | 0.88 | LOXL2 (0.53) | LOXL2MC4RIDO1DPP4DPP7 | |
| SCHEMBL17848993 | 0.82 | LOXL2 (0.44) | LOXL2MC4RIDO1DPP4DPP7 | |
| SCHEMBL6563037 | 0.79 | LOXL2 (0.50) | LOXL2MC4RIDO1DPP4DPP7 | |
| SCHEMBL6889395 | 0.76 | LOXL2 (0.62) | LOXL2IDO1TSHRLMNAALDH1A1 | |
| SCHEMBL5148823 | 0.75 | LOXL2 (0.60) | LOXL2MC4RIDO1DPP4DPP7 | |
| Hydrochloric Acid SCHEMBL9476171 | 0.75 | LOXL2 (0.60) | LOXL2IDO1TSHRLMNAALDH1A1 | |
| SCHEMBL514488 | 0.75 | LOXL2 (0.60) | LOXL2MC4RIDO1DPP4DPP7 | |
| SCHEMBL8829958 | 0.74 | LOXL2 (0.50) | LOXL2MC4RIDO1MMP2TSHR | |
| Hydrochloric Acid SCHEMBL9355954 | 0.73 | LOXL2 (0.58) | LOXL2MC4RIDO1DPP4DPP7 | |
| SCHEMBL18069332 | 0.73 | LOXL2 (0.48) | LOXL2IDO1TSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650134-A | Peptides | NOVARTIS AG (FORMERLY SANDOZ LTD.) (CH) | 1997-07-22 | — | — | US | disclosed |
| EP-0607103-A2 | Somatostatin analogs containing chelating groups and their radiolabeled compositions | SANDOZ LTD. (CH) | 1994-07-20 | — | — | EP | disclosed |